The effectiveness of vitamin D deficiency supplementation in the obese by the stimulation of cutaneous synthesis with UVB
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 1
Abstract
Obese people are predisposed to vitamin D deficiency. The cause of vitamin D deficiency is inadequate solar radiation (containing the UVB faction responsible for the synthesis of the vitamin D in the skin), impaired vitamin D skin synthesis or sequestration of the vitamin D in the fatty tissue.<br>The objective of this study was to show how effective is cutaneous synthesis of vitamin D measured as calcifediol concentration (as a marker of vitamin D adequacy) before and after (in 4, 7, 14, 21 days) vitamin D supplementation after the stimulation of cutaneous synthesis with UVB irradiation in 40 obese and 30 nonobese individuals.<br>The mean concentration of vitamin D at the beginning did not differ significantly (15.5 ng/ml in the obese vs 15.4 ng/ml in control group). The increase of 25(OH)D<sub>3</sub> after UVB irradiation in the obese and nonobese also did not differ. The largest change was observed 14 days after exposure (in the obese 4,88 ng/ml, in the control group 5.42 ng/ml). In conclusion, the cutaneous synthesis of vitamin D is effective.
Authors and Affiliations
Michał Wąsowski, Ewa Marcinowska-Suchowierska
Keywords
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