The Efficacy and Safety of Rapid Antigen Detection Test in Adults: A Retrospective Study
Journal Title: Eurasian Journal of Family Medicine - Year 2018, Vol 7, Issue 2
Abstract
Aim: Acute respiratory infections are one of the diseases in which antibiotics are inappropriately used. Our study aim was to define the efficacy and safety of the rapid antigen detection test in decreasing the inappropriate use of antibiotics in adults. Methods: This was a retrospective study on patients over 15 years of age who came to our clinic because of sore throat from September 2016 to 2017. Data on culture, rapid antigen detection test results, and the prescribed drugs were recorded from their files and were expressed as frequencies. Statistical analyses were performed by the Chi-square test and Student’s t-test, with p <0.05 accepted as statistically significant. Results: Among a total of 2426 patients, the rapid antigen detection test and culture results had a perfect fit (κ=0.911) and had no statistically significant differences (p=0.125). Using culture as the standard, the rapid antigen detection test had a sensitivity of 86.4%, specificity of 99.9%, positive predictive value of 97.4%, negative predictive value of 99.2%, and correct awareness rate of 99.1%. Conclusion: The use of rapid antigen detection test in cases with pharyngitis could make antibiotic prescription safe and appropriate.
Authors and Affiliations
Güzin Zeren Öztürk, Dilek Toprak
Keywords
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