Therapeutic effects of two types of interbody fusions on degenerative lumbar spondylolisthesis in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics

Journal Title: Chinese Journal of Clinical Research - Year 2024, Vol 37, Issue 1

Abstract

<b>Objective</b> To evaluate the therapeutic effects of oblique lateral interbody fusion (OLIF) and minimally invasive transforminal lumbar interbody fusion (MIS-TLIF) on degenerative lumbar spondylolisthesis (DLS) in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics. <b>Methods</b> A retrospective study was conducted on 122 elderly patients with DLS who underwent surgical treatment in Cangzhou Hospital of Integrated Chinese and Western Medicine from April 2020 to March 2022. Fifty-nine patients who received OLIF surgery were as OLIF group, while 63 patients who received MIS-TLIF surgery were as MIS-TLIF group. The clinical data of operation, pre-operation, immediately after operation and 12 months after operation were collected from two groups of patients, including the spondylolisthesis parameters [intervertebral height (DH), local kyphosis angle (SK), lumbar spondylolisthesis rate (SP), spondylolisthesis angle (SA)], lumbar pelvic anatomical parameters [L1 distance between the center of the vertebral body and the perpendicular line of the sacrum (LASD), lumbar lordosis angle (LL), sacral inclination angle (SS), pelvic inclination angle (PT) and pelvic incidence angle (PI)]. Visual Analogue Scale for Pain (VAS) score and the Oswestry Dysfunction Index (ODI) were used to assesse pain perception and lumbar function. <b>Results</b> Compared with the MIS-TLIF group, the OLIF group had shorter operative time, hospital stay and incision length, less intraoperative bleeding and postoperative drainage flow (P<0.01). In immediate period and 1 year after surgery compared to preoperative levels, both groups of patients showed an increase in DH, a decrease in SK, SP and SA (P<0.05), and a significant decrease in LASD and PT, a significant increase in LL and SS (P<0.05), but no significant change in PI (P>0.05); the VAS score and ODI decreased significantly (P<0.05). At the same time point after surgery, the OLIF group had a larger DH and a smaller SK compared with the MIS-TLIF group (P<0.01), and there was no significant difference in other mechanical parameters of spondylolisthesis, lumbar pelvic anatomy parameters, VAS score and ODI between the two groups (P>0.05). <b>Conclusion</b> OLIF and MIS-TLIF have good improvement effects on the spine pelvic anatomy, mechanical parameters of lumbar spondylolisthesis, pain degree, and lumbar function in elderly patients with DLS, and the effects are similar, but when using OLIF, the operation time, hospitalization time, and incision length are shorter, and the intraoperative blood loss and postoperative drainage are less, which has obvious advantages

Authors and Affiliations

LIU Yang, WANG Zhiwei, ZHAO Chong, WANG Yan

Keywords

Related Articles

Correlation between skeletal muscle mass and islet function in patients with type 2 diabetes mellitus

"<b>Objective</b> To investigate the correlation between skeletal muscle mass and islet function, skeletal muscle mass and insulin resistance in patients with type 2 diabetes mellitus (T2DM), and to elaborate on the clin...

Research progress of amino acid metabolism regulating PI3K/AKT/mTOR signaling pathway in gastric cancer

In the tumor microenvironment, amino acids are important nutrients constituting immune cells and tumor cells. Some proteins or key enzymes in the metabolism process are expected to become tumor diagnostic markers or ther...

Research progress of gene detection in systemic therapy of pancreatic cancer

Pancreatic cancer is a common highly malignant digestive tract tumor. Due to its location and disease characteristics, it presents significant challenges in treatment. The molecular diversity of pancreatic cancer contrib...

Efficacy of unilateral biportal endoscopy versus unilateral endoscopiy in the treatment of lumbar degenerative diseases: a Meta-analysis

<b>Objective</b> Meta-analysis was used to compare the efficacy of unilateral biportal endoscopy (UBE) and unilateral endoscopy(UE) in the treatment of lumbar degenerative diseases (LDD), in order to provide a reference...

Relationship between gut microbiota and hepatocellular carcinoma through two-sample Mendelian randomization study

Objective To investigate the potential association between 221 types of gut microbiota and hepatocellular carcinoma (HCC) using a two-sample Mendelian randomization approach, providing insights for the prevention and tre...

Download PDF file
  • EP ID EP735809
  • DOI 10.13429/j.cnki.cjcr.2024.01.017
  • Views 35
  • Downloads 0

How To Cite

LIU Yang, WANG Zhiwei, ZHAO Chong, WANG Yan (2024). Therapeutic effects of two types of interbody fusions on degenerative lumbar spondylolisthesis in the elderly based on spinal pelvic anatomy and lumbar spondylolisthesis mechanics. Chinese Journal of Clinical Research, 37(1), -. https://europub.co.uk./articles/-A-735809