Role of Diffusion Weighted MRI in Evaluation of Urinary Bladder Cancer in Iraqi Patient in Correlation with Histopathological Grade.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 2
Abstract
Background: Bladder cancer is a common urologic cancer that has the highest recurrence rate of any malignancy. MRI (magnetic resonance imaging) is a vital complementary diagnostic device in the diagnosis, staging, and follow up of bladder cancer. Objectives: The main purpose of this study was to explore the diagnostic effectiveness of pelvic MRI including ADC (apparent diffusion coefficient) and DWI (diffusion weighted imaging) in the assessment of bladder cancer grade and thus helping in patients' management. Methods: A cross sectional study comprised forty preoperative patients complaining of hematuria referred to the urology consulting clinic in martyr Ghazi Al-Hariri hospital in Baghdad during the period from January 2015 to September 2016. Their age ranged from 43 to 74 years. Their MRI findings were reviewed and correlated with the corresponding histopathology results. Results:By reviewing the MRI finding in forty patients ,we see that 60% show low grade tumor ,while 40% had high grade tumor this is classified according to their ADC map which revealed that all patients with high grade tumor had their tumor is above 9x10-3mm 2 /second while those with low grade tumor had value greater than above value, wall invasion on T2WI ( T2 weighted imaging) is seen in 33% of low grade tumor and 81% of high grade tumor, in contrary to DWI that identify wall invasion in 21% and 43% of the tumors respectively. Conclusion: ADC map and DWI using b-value of 0 and 1000 respectively are of greater value in localization, evaluation and prediction of histological grade of bladder cancer.
Authors and Affiliations
Dr. Khaleel Ibraheem Mohson,, Bassil Ismail, MBChB, CABMS(uro), Dr. Sura Tami Abduljabbar ,MBChB3
Keywords
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- EP ID EP388554
- DOI 10.9790/3008-1202027477
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