Significance of morphological study of cataract lens - An observational study with literature review
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 9, Issue 2
Abstract
Background: Cataract is a visible opacity in the lens substance that leads to visual impairment. Surgery is the treatment of choice for cataract and it is of interesting that the colour of the enucleated cataract lens varies. Objective: This study was aimed to observe the morphological changes in different colour cataract lenses (nucleus) to find its significance and pathogenic mechanism. Materials and Methods: 104 cataract lenses (nucleus) were studied for gross findings of diameter, thickness, colour and histological appearances with routine H&E stain. Random selection of different colour lenses (n=67) were studied with Von kossa special stain for calcium deposits. All these observations along with demographic data of age, sex were correlated. Results: Out of 104 lenses, 60 were from females and 44 from males and the predominant age group were between 51-60 years (n=41; 39.4%). The mean diameter was 8mm and thickness was 2.4mm.The colour of the lenses varied from cream, yellow ,honey to brown with predominance of creamy yellow (n=34 ;32.7%).The histological appearance showed predominance of mixed pattern of central homogenous with peripheral lamellated bands (n=71; 68.3%) and it was significantly associated with cream and creamy yellow colour(p-0.048).Special stain sections showed different morphological forms of calcification in varied intensity and it was significantly associated with cataract.(n=57 ;85%)There was no significant association of lens colour with age, sex and intensity of calcification. Conclusion: There was a significant association of pathological calcification in cataract lens and it plays a role in the pathogenesis of cataract. There was no correlation between lens colour and calcification.
Authors and Affiliations
Sumathi S, Venkatesan M J
Keywords
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- EP ID EP457102
- DOI 10.26611/105922
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